tert-Butyl 3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)pyrrolidine-1-carboxylate
98%
- Product Code: 152390
CAS:
1359974-18-7
| Molecular Weight: | 363.26 g./mol | Molecular Formula: | C₁₈H₃₀BN₃O₄ |
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| EC Number: | MDL Number: | MFCD22570722 | |
| Melting Point: | Boiling Point: | 479.4±35.0 °C at 760 mmHg | |
| Density: | Storage Condition: | Room temperature, seal, dry |
Product Description:
Used primarily as an intermediate in pharmaceutical synthesis, especially in Suzuki-Miyaura cross-coupling reactions. Its pyrazole ring and boronate ester group enable efficient formation of carbon-carbon bonds, making it valuable in constructing complex heterocyclic systems found in bioactive molecules. Commonly employed in the development of kinase inhibitors and other drug candidates where nitrogen-containing heterocycles are key structural elements. The tert-butyl carbamate (Boc) protecting group allows for selective deprotection under mild acidic conditions, facilitating stepwise synthesis in peptide-like frameworks. Suitable for use in medicinal chemistry and R&D settings requiring high-purity boronic ester building blocks.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 100mg | 10-20 days | $88.18 |
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| 250mg | 10-20 days | $180.68 |
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| 1g | 10-20 days | $473.58 |
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| 5g | 10-20 days | $1,792.88 |
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tert-Butyl 3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)pyrrolidine-1-carboxylate
Used primarily as an intermediate in pharmaceutical synthesis, especially in Suzuki-Miyaura cross-coupling reactions. Its pyrazole ring and boronate ester group enable efficient formation of carbon-carbon bonds, making it valuable in constructing complex heterocyclic systems found in bioactive molecules. Commonly employed in the development of kinase inhibitors and other drug candidates where nitrogen-containing heterocycles are key structural elements. The tert-butyl carbamate (Boc) protecting group allows for selective deprotection under mild acidic conditions, facilitating stepwise synthesis in peptide-like frameworks. Suitable for use in medicinal chemistry and R&D settings requiring high-purity boronic ester building blocks.
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