(3-Bromobicyclo[1.1.1]pentan-1-yl)methanol
97%
- Product Code: 152417
CAS:
137741-16-3
| Molecular Weight: | 177.04 g./mol | Molecular Formula: | C₆H₉BrO |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD31705883 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | Room temperature, inert gas |
Product Description:
Used primarily as a building block in medicinal chemistry, this compound enables the synthesis of highly strained, three-dimensional structures that improve drug potency and metabolic stability. Its unique bridged architecture is valuable in the design of bioisosteres, particularly as a replacement for phenyl or tert-butyl groups, enhancing pharmacokinetic properties in drug candidates. It is especially useful in the development of CNS-targeted therapeutics due to its ability to increase saturation and reduce planarity, which can improve blood-brain barrier penetration. Additionally, the hydroxyl group allows for further functionalization, facilitating conjugation or linker attachment in prodrug strategies and targeted therapies.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 50mg | 10-20 days | $583.33 |
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| 100mg | 10-20 days | $918.26 |
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| 250mg | 10-20 days | $1,851.58 |
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(3-Bromobicyclo[1.1.1]pentan-1-yl)methanol
Used primarily as a building block in medicinal chemistry, this compound enables the synthesis of highly strained, three-dimensional structures that improve drug potency and metabolic stability. Its unique bridged architecture is valuable in the design of bioisosteres, particularly as a replacement for phenyl or tert-butyl groups, enhancing pharmacokinetic properties in drug candidates. It is especially useful in the development of CNS-targeted therapeutics due to its ability to increase saturation and reduce planarity, which can improve blood-brain barrier penetration. Additionally, the hydroxyl group allows for further functionalization, facilitating conjugation or linker attachment in prodrug strategies and targeted therapies.
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