tert-Butyl 4-(bromomethyl)-3,3-difluoropiperidine-1-carboxylate
98%
- Product Code: 152425
CAS:
1303974-03-9
| Molecular Weight: | 314.17 g./mol | Molecular Formula: | C₁₁H₁₈BrF₂NO₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD18909766 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | Room temperature, dry |
Product Description:
Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of bioactive molecules targeting central nervous system disorders. Its structure allows for selective modifications, making it valuable in constructing fluorinated piperidine derivatives that enhance metabolic stability and binding affinity in drug candidates. Commonly employed in medicinal chemistry for creating analogs in structure-activity relationship (SAR) studies. The bromomethyl group serves as a reactive handle for further functionalization, enabling coupling reactions with nucleophiles to form ether, amine, or thioether linkages. Also utilized in the preparation of protease inhibitors and receptor modulators where fluorination improves pharmacokinetic properties.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 50mg | 10-20 days | ฿9,350.00 |
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| 100mg | 10-20 days | ฿15,880.00 |
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| 250mg | 10-20 days | ฿28,300.00 |
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| 1g | 10-20 days | ฿86,660.00 |
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tert-Butyl 4-(bromomethyl)-3,3-difluoropiperidine-1-carboxylate
Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of bioactive molecules targeting central nervous system disorders. Its structure allows for selective modifications, making it valuable in constructing fluorinated piperidine derivatives that enhance metabolic stability and binding affinity in drug candidates. Commonly employed in medicinal chemistry for creating analogs in structure-activity relationship (SAR) studies. The bromomethyl group serves as a reactive handle for further functionalization, enabling coupling reactions with nucleophiles to form ether, amine, or thioether linkages. Also utilized in the preparation of protease inhibitors and receptor modulators where fluorination improves pharmacokinetic properties.
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