tert-Butyl 3-fluoro-4-hydroxy-4-(trifluoromethyl)piperidine-1-carboxylate
97%
- Product Code: 153094
CAS:
2101206-18-0
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| Density: | Storage Condition: | 2-8°C, dry |
Product Description:
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of central nervous system (CNS) active compounds. Its structural features, including the fluorinated and hydroxylated piperidine core, make it valuable for enhancing metabolic stability and binding affinity in drug candidates. Commonly employed in the preparation of neurokinin receptor antagonists and other bioactive molecules where modulation of brain permeability and target selectivity is required. The tert-butoxycarbonyl (Boc) protecting group allows for selective functionalization during multi-step syntheses, enabling efficient route design in medicinal chemistry.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 100mg | 10-20 days | ฿12,700.00 |
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| 250mg | 10-20 days | ฿21,070.00 |
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| 1g | 10-20 days | ฿68,010.00 |
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tert-Butyl 3-fluoro-4-hydroxy-4-(trifluoromethyl)piperidine-1-carboxylate
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of central nervous system (CNS) active compounds. Its structural features, including the fluorinated and hydroxylated piperidine core, make it valuable for enhancing metabolic stability and binding affinity in drug candidates. Commonly employed in the preparation of neurokinin receptor antagonists and other bioactive molecules where modulation of brain permeability and target selectivity is required. The tert-butoxycarbonyl (Boc) protecting group allows for selective functionalization during multi-step syntheses, enabling efficient route design in medicinal chemistry.
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