tert-Butyl (4-(3-(dimethoxyphosphoryl)-2-oxopropyl)phenyl)carbamate

98%

  • Product Code: 153375
  CAS:    494224-44-1
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Density: Storage Condition: 2-8°C, dry
Product Description: Used in pharmaceutical synthesis as a protected intermediate, particularly in the development of kinase inhibitors and other bioactive molecules. The tert-butyl carbamate (Boc) group provides amine protection during peptide or heterocycle assembly, while the dimethoxyphosphoryl moiety allows for further functionalization via Horner-Wadsworth-Emmons olefination or phosphorylation reactions. Its structure supports the construction of complex drug candidates requiring selective reactivity and stability under multi-step synthesis conditions. Commonly employed in medicinal chemistry for optimizing metabolic stability and target binding affinity.
Sizes / Availability / Pricing:
Size Availability Price Quantity
0.025 10-20 days $581.24
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-
0.050 10-20 days $1,046.63
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-
0.100 10-20 days $1,960.34
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tert-Butyl (4-(3-(dimethoxyphosphoryl)-2-oxopropyl)phenyl)carbamate
Used in pharmaceutical synthesis as a protected intermediate, particularly in the development of kinase inhibitors and other bioactive molecules. The tert-butyl carbamate (Boc) group provides amine protection during peptide or heterocycle assembly, while the dimethoxyphosphoryl moiety allows for further functionalization via Horner-Wadsworth-Emmons olefination or phosphorylation reactions. Its structure supports the construction of complex drug candidates requiring selective reactivity and stability under multi-step synthesis conditions. Commonly employed in medicinal chemistry for optimizing metabolic stability and target binding affinity.
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