4-Bromo-2-Chloro-1-Isothiocyanatobenzene
98%
- Product Code: 154036
CAS:
98041-69-1
| Molecular Weight: | 248.53 g./mol | Molecular Formula: | C₇H₃BrClNS |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00041051 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C |
Product Description:
Used as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in the development of bioactive molecules that require selective functionalization of aromatic rings. Its isothiocyanate group readily reacts with amines and thiols, making it valuable in the preparation of thiourea derivatives and heterocyclic compounds. It is also employed in medicinal chemistry for constructing kinase inhibitors and antimicrobial agents. Due to the presence of multiple halogen atoms, it serves as a versatile building block in cross-coupling reactions such as Suzuki and Heck reactions, enabling the formation of complex aromatic structures. Additionally, it finds use in the development of covalent inhibitors where the isothiocyanate acts as an electrophilic warhead targeting nucleophilic residues in proteins.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | €15.64 |
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| 1.000 | 10-20 days | €33.13 |
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| 5.000 | 10-20 days | €157.96 |
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| 25.000 | 10-20 days | €721.44 |
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4-Bromo-2-Chloro-1-Isothiocyanatobenzene
Used as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in the development of bioactive molecules that require selective functionalization of aromatic rings. Its isothiocyanate group readily reacts with amines and thiols, making it valuable in the preparation of thiourea derivatives and heterocyclic compounds. It is also employed in medicinal chemistry for constructing kinase inhibitors and antimicrobial agents. Due to the presence of multiple halogen atoms, it serves as a versatile building block in cross-coupling reactions such as Suzuki and Heck reactions, enabling the formation of complex aromatic structures. Additionally, it finds use in the development of covalent inhibitors where the isothiocyanate acts as an electrophilic warhead targeting nucleophilic residues in proteins.
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| Heat Resistance | - |
| Stable in pH range | - |
| Solubility | - |
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| INCI | - |
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