1-Bromo-2-Ethynyl-4-(Trifluoromethoxy)Benzene
95%
- Product Code: 154271
CAS:
2379918-32-6
| Molecular Weight: | 265.03 g./mol | Molecular Formula: | C₉H₄BrF₃O |
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| Density: | Storage Condition: | Room temperature |
Product Description:
Used as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in reactions involving palladium-catalyzed couplings such as Sonogashira and Suzuki reactions. Its ethynyl and bromo functional groups allow for selective and sequential bond formation, enabling the construction of complex aromatic and heterocyclic systems. The presence of the trifluoromethoxy group enhances lipophilicity and metabolic stability in bioactive molecules, making this compound valuable in medicinal chemistry for developing compounds with improved pharmacokinetic properties. It is also employed in the preparation of fluorinated organic materials and liquid crystals where electronic and thermal stability are important.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 100mg | 10-20 days | ฿660.00 |
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| 250mg | 10-20 days | ฿1,560.00 |
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| 1g | 10-20 days | ฿5,940.00 |
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1-Bromo-2-Ethynyl-4-(Trifluoromethoxy)Benzene
Used as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in reactions involving palladium-catalyzed couplings such as Sonogashira and Suzuki reactions. Its ethynyl and bromo functional groups allow for selective and sequential bond formation, enabling the construction of complex aromatic and heterocyclic systems. The presence of the trifluoromethoxy group enhances lipophilicity and metabolic stability in bioactive molecules, making this compound valuable in medicinal chemistry for developing compounds with improved pharmacokinetic properties. It is also employed in the preparation of fluorinated organic materials and liquid crystals where electronic and thermal stability are important.
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