(Bromodifluoromethyl)triphenylphosphonium Bromide

≥95%

  • Product Code: 154925
  CAS:    58201-66-4
Molecular Weight: 472.1 g./mol Molecular Formula: C₁₉H₁₅Br₂F₂P
EC Number: MDL Number: MFCD00191843
Melting Point: Boiling Point:
Density: Storage Condition: 2-8°C, light-proof, inert gas
Product Description: Used as a reagent in organic synthesis for the introduction of the bromodifluoromethyl group (–CF2Br) into organic molecules. This transformation is valuable in the preparation of fluorinated compounds that serve as intermediates in pharmaceuticals, agrochemicals, and materials science. The phosphonium salt facilitates the formation of difluorocarbene or related species under basic conditions, enabling efficient C–H difluoromethylation or cyclopropanation reactions. Its utility in generating fluorinated building blocks makes it particularly important in medicinal chemistry for modulating the metabolic stability, lipophilicity, and bioavailability of drug candidates.
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Size Availability Price Quantity
250mg 10-20 days ฿17,000.00
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(Bromodifluoromethyl)triphenylphosphonium Bromide
Used as a reagent in organic synthesis for the introduction of the bromodifluoromethyl group (–CF2Br) into organic molecules. This transformation is valuable in the preparation of fluorinated compounds that serve as intermediates in pharmaceuticals, agrochemicals, and materials science. The phosphonium salt facilitates the formation of difluorocarbene or related species under basic conditions, enabling efficient C–H difluoromethylation or cyclopropanation reactions. Its utility in generating fluorinated building blocks makes it particularly important in medicinal chemistry for modulating the metabolic stability, lipophilicity, and bioavailability of drug candidates.
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