7-Cyclopentyl-5-(4-methoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
98%
- Product Code: 156940
CAS:
344359-25-7
Molecular Weight: | 308.4 g./mol | Molecular Formula: | C₁₈H₂₀N₄O |
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EC Number: | MDL Number: | MFCD34565083 | |
Melting Point: | Boiling Point: | ||
Density: | Storage Condition: | -20°C, Sealed, Dry |
Product Description:
Used as a potent and selective inhibitor of cyclin-dependent kinases (CDKs), particularly CDK4 and CDK6, this compound plays a key role in cancer research. It interferes with the cell cycle progression in tumor cells, especially those with dysregulated retinoblastoma (Rb) protein pathways, leading to cell cycle arrest and inhibition of proliferation. It is widely applied in preclinical studies for evaluating therapies against breast cancer, leukemia, and other malignancies dependent on CDK4/6 activity. Its ability to selectively target cancer cells while sparing normal cells makes it a valuable tool in developing targeted oncology treatments.
Sizes / Availability / Pricing:
Size | Availability | Price | Quantity |
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1mg | 10-20 days | ฿2,930.00 |
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5mg | 10-20 days | ฿10,250.00 |
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10mg | 10-20 days | ฿15,370.00 |
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7-Cyclopentyl-5-(4-methoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
Used as a potent and selective inhibitor of cyclin-dependent kinases (CDKs), particularly CDK4 and CDK6, this compound plays a key role in cancer research. It interferes with the cell cycle progression in tumor cells, especially those with dysregulated retinoblastoma (Rb) protein pathways, leading to cell cycle arrest and inhibition of proliferation. It is widely applied in preclinical studies for evaluating therapies against breast cancer, leukemia, and other malignancies dependent on CDK4/6 activity. Its ability to selectively target cancer cells while sparing normal cells makes it a valuable tool in developing targeted oncology treatments.
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