C188-9
10mM in DMSO
- Product Code: 157844
CAS:
432001-19-9
| Molecular Weight: | 471.52 g./mol | Molecular Formula: | C₂₇H₂₁NO₅S |
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| Density: | Storage Condition: | -20°C |
Product Description:
C188-9 is primarily investigated for its potential as a small-molecule inhibitor targeting cancer cells, particularly through the suppression of STAT3 (Signal Transducer and Activator of Transcription 3) signaling. This pathway is often constitutively active in various tumors and contributes to cell proliferation, survival, and immune evasion. By inhibiting STAT3 activation, C188-9 has shown promise in preclinical studies for treating cancers such as lung, breast, and pancreatic carcinomas.
It has demonstrated anti-tumor effects by inducing apoptosis and reducing tumor growth in animal models. Additionally, C188-9 may enhance the efficacy of other anti-cancer therapies, including chemotherapy and immunotherapy, due to its role in modulating the tumor microenvironment. Research is ongoing to evaluate its pharmacokinetics, toxicity profile, and potential for clinical development.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1ml | 10-20 days | ฿8,080.00 |
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C188-9
C188-9 is primarily investigated for its potential as a small-molecule inhibitor targeting cancer cells, particularly through the suppression of STAT3 (Signal Transducer and Activator of Transcription 3) signaling. This pathway is often constitutively active in various tumors and contributes to cell proliferation, survival, and immune evasion. By inhibiting STAT3 activation, C188-9 has shown promise in preclinical studies for treating cancers such as lung, breast, and pancreatic carcinomas.
It has demonstrated anti-tumor effects by inducing apoptosis and reducing tumor growth in animal models. Additionally, C188-9 may enhance the efficacy of other anti-cancer therapies, including chemotherapy and immunotherapy, due to its role in modulating the tumor microenvironment. Research is ongoing to evaluate its pharmacokinetics, toxicity profile, and potential for clinical development.
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