4-Chloro-2-fluorobenzene-1-sulfonyl chloride
98%
- Product Code: 160768
CAS:
141337-26-0
| Molecular Weight: | 229.06 g./mol | Molecular Formula: | C₆H₃Cl₂FO₂S |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | 34-38°C | Boiling Point: | |
| Density: | Storage Condition: | 2-8°C |
Product Description:
Widely used as an intermediate in the synthesis of agrochemicals and pharmaceuticals, this compound serves as a sulfonylating agent to introduce the 4-chloro-2-fluorobenzenesulfonyl group into target molecules. It is particularly valuable in the development of herbicides and fungicides due to the electron-withdrawing nature of the chloro and fluoro substituents, which enhance the stability and bioactivity of the final products. In medicinal chemistry, it participates in the preparation of sulfonamide-based drug candidates, where the sulfonyl chloride group reacts readily with amines under mild conditions. Its selectivity and reactivity make it suitable for multi-step syntheses requiring functional group tolerance. Handling requires caution due to its moisture sensitivity and potential to release hydrogen chloride upon hydrolysis.
Product Specification:
| Test | Specification |
|---|---|
| APPEARANCE | Off-white to light yellow Solid |
| Purity (%) | 97.5-100 |
| Infrared Spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.250 | 10-20 days | ฿290.00 |
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| 1.000 | 10-20 days | ฿216.00 |
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| 5.000 | 10-20 days | ฿612.00 |
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4-Chloro-2-fluorobenzene-1-sulfonyl chloride
Widely used as an intermediate in the synthesis of agrochemicals and pharmaceuticals, this compound serves as a sulfonylating agent to introduce the 4-chloro-2-fluorobenzenesulfonyl group into target molecules. It is particularly valuable in the development of herbicides and fungicides due to the electron-withdrawing nature of the chloro and fluoro substituents, which enhance the stability and bioactivity of the final products. In medicinal chemistry, it participates in the preparation of sulfonamide-based drug candidates, where the sulfonyl chloride group reacts readily with amines under mild conditions. Its selectivity and reactivity make it suitable for multi-step syntheses requiring functional group tolerance. Handling requires caution due to its moisture sensitivity and potential to release hydrogen chloride upon hydrolysis.
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