Cyclic Pifithrin-α Hydrobromide
≥98%
- Product Code: 161186
CAS:
511296-88-1
Molecular Weight: | 349.29 g./mol | Molecular Formula: | C₁₆H₁₆N₂S·HBr |
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EC Number: | MDL Number: | MFCD02683960 | |
Melting Point: | Boiling Point: | ||
Density: | Storage Condition: | -20°C |
Product Description:
Used primarily as a research compound in cellular and molecular biology, this chemical acts as a reversible inhibitor of p53, a tumor suppressor protein involved in cell cycle regulation and apoptosis. By temporarily suppressing p53 activity, it allows scientists to study the role of p53 in stress responses, DNA damage, and cell death pathways. It is particularly valuable in experiments where transient inhibition of p53 is needed to improve cell survival during stressful laboratory procedures such as cell culture, transfection, or cryopreservation. Its reversible nature makes it advantageous over permanent inhibitors, enabling restoration of normal p53 function after treatment. Commonly applied in studies related to cancer, neurodegeneration, and aging.
Product Specification:
Test | Specification |
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Appearance | White to Off-White Powder or Crystals |
Purity (HPLC) | 98.0-100% |
Infrared Spectrum | Conforms to Structure |
NMR | Conforms to Structure |
Sizes / Availability / Pricing:
Size | Availability | Price | Quantity |
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20mg | 10-20 days | ฿5,220.00 |
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100mg | 10-20 days | ฿10,590.00 |
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250mg | 10-20 days | ฿15,830.00 |
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Cyclic Pifithrin-α Hydrobromide
Used primarily as a research compound in cellular and molecular biology, this chemical acts as a reversible inhibitor of p53, a tumor suppressor protein involved in cell cycle regulation and apoptosis. By temporarily suppressing p53 activity, it allows scientists to study the role of p53 in stress responses, DNA damage, and cell death pathways. It is particularly valuable in experiments where transient inhibition of p53 is needed to improve cell survival during stressful laboratory procedures such as cell culture, transfection, or cryopreservation. Its reversible nature makes it advantageous over permanent inhibitors, enabling restoration of normal p53 function after treatment. Commonly applied in studies related to cancer, neurodegeneration, and aging.
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