5-Chlorosaligenyl-N,N-diisopropylphosphoramidite
95%
- Product Code: 161212
CAS:
1620086-77-2
| Molecular Weight: | 287.72 g./mol | Molecular Formula: | C₁₃H₁₉ClNO₂P |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | 45°C | Boiling Point: | |
| Density: | Storage Condition: | 2~8℃, stored in inert gas |
Product Description:
Used in the synthesis of oligonucleotides, particularly in the preparation of modified DNA or RNA strands for research and therapeutic applications. Acts as a phosphitylating agent to introduce phosphoramidite linkages during solid-phase oligonucleotide synthesis. The chlorosaligenyl group enhances stability and reactivity, making it suitable for automated synthesis platforms. Commonly employed in the development of antisense oligonucleotides, siRNA, and other nucleic acid-based drugs where precise chemical modifications are required to improve nuclease resistance and binding affinity.
Product Specification:
| Test | Specification |
|---|---|
| Appearance | White to Off-white Powder or Crystals |
| Purity (%) | 94.5-100 |
| Infrared Spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 200mg | 10-20 days | €137.04 |
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5-Chlorosaligenyl-N,N-diisopropylphosphoramidite
Used in the synthesis of oligonucleotides, particularly in the preparation of modified DNA or RNA strands for research and therapeutic applications. Acts as a phosphitylating agent to introduce phosphoramidite linkages during solid-phase oligonucleotide synthesis. The chlorosaligenyl group enhances stability and reactivity, making it suitable for automated synthesis platforms. Commonly employed in the development of antisense oligonucleotides, siRNA, and other nucleic acid-based drugs where precise chemical modifications are required to improve nuclease resistance and binding affinity.
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