4-Chloro-5H-pyrrolo[3,2-d]pyrimidin-2-amine
97%
- Product Code: 161835
CAS:
943736-58-1
| Molecular Weight: | 168.58 g./mol | Molecular Formula: | C₆H₅ClN₄ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD09800375 | |
| Melting Point: | Boiling Point: | 472.3°C at 760 mmHg | |
| Density: | Storage Condition: | 2-8°C, protected from light, stored in inert gas |
Product Description:
Used as a key intermediate in the synthesis of kinase inhibitors, particularly in the development of anticancer agents. Its structure allows selective binding to ATP sites in protein kinases, making it valuable in targeted therapies for cancers such as leukemia and non-small cell lung cancer. Also employed in the preparation of JAK2 and EGFR inhibitors. Commonly modified at the 4-chloro and 2-amino positions to enhance potency, selectivity, and pharmacokinetic properties in drug candidates. Widely utilized in medicinal chemistry research for structure-activity relationship (SAR) studies.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 250mg | 10-20 days | ฿4,030.00 |
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| 1g | 10-20 days | ฿13,520.00 |
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| 5g | 10-20 days | ฿43,880.00 |
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4-Chloro-5H-pyrrolo[3,2-d]pyrimidin-2-amine
Used as a key intermediate in the synthesis of kinase inhibitors, particularly in the development of anticancer agents. Its structure allows selective binding to ATP sites in protein kinases, making it valuable in targeted therapies for cancers such as leukemia and non-small cell lung cancer. Also employed in the preparation of JAK2 and EGFR inhibitors. Commonly modified at the 4-chloro and 2-amino positions to enhance potency, selectivity, and pharmacokinetic properties in drug candidates. Widely utilized in medicinal chemistry research for structure-activity relationship (SAR) studies.
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