CIS-TETRACHLORODIAMMINE PLATINUM (IV)

roplatinum(IV), Pt 52.6%

  • Product Code: 162721
  CAS:    16893-06-4
Molecular Weight: 370.95 g./mol Molecular Formula: Cl₄H₆N₂Pt
EC Number: MDL Number: MFCD00050045
Melting Point: >300 °C(lit.) Boiling Point:
Density: Storage Condition: 2-8°C, sealed, dry
Product Description: Used primarily as an intermediate in the synthesis of platinum-based anticancer drugs. It serves in the development of chemotherapeutic agents due to its ability to undergo reduction and release active platinum species that can bind to DNA. This interaction disrupts DNA replication and transcription, leading to apoptosis in rapidly dividing cells, particularly cancer cells. Its stability in the +4 oxidation state allows for controlled activation under physiological conditions, making it valuable in designing targeted drug delivery systems. Also investigated for use in combination therapies to overcome drug resistance in tumors.
Sizes / Availability / Pricing:
Size Availability Price Quantity
100mg 10-20 days £51.76
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250mg 10-20 days £119.48
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1g 10-20 days £357.76
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CIS-TETRACHLORODIAMMINE PLATINUM (IV)
Used primarily as an intermediate in the synthesis of platinum-based anticancer drugs. It serves in the development of chemotherapeutic agents due to its ability to undergo reduction and release active platinum species that can bind to DNA. This interaction disrupts DNA replication and transcription, leading to apoptosis in rapidly dividing cells, particularly cancer cells. Its stability in the +4 oxidation state allows for controlled activation under physiological conditions, making it valuable in designing targeted drug delivery systems. Also investigated for use in combination therapies to overcome drug resistance in tumors.
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