5-Chloro-3-methylbenzo[b]thiophene- 2-sulfonamide
95%
- Product Code: 163624
CAS:
190659-59-7
| Molecular Weight: | 261.75 g./mol | Molecular Formula: | C₉H₈ClNO₂S₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00210142 | |
| Melting Point: | Boiling Point: | 470.2±55.0 °C(Predicted) | |
| Density: | 1.537±0.06 g/cm3(Predicted) | Storage Condition: | Room temperature |
Product Description:
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of carbonic anhydrase inhibitors. These inhibitors are applied in the treatment of glaucoma, epilepsy, and certain types of edema. The sulfonamide group enhances binding to the carbonic anhydrase enzyme, while the chloro and methyl substitutions improve metabolic stability and selectivity. Its lipophilic character aids in membrane penetration, making it suitable for drugs requiring central nervous system access. Also explored in antimicrobial and anticancer research due to its ability to modulate enzyme activity in pathological cells.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | ฿990.00 |
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| 0.250 | 10-20 days | ฿1,730.00 |
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| 1.000 | 10-20 days | ฿3,580.00 |
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5-Chloro-3-methylbenzo[b]thiophene- 2-sulfonamide
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of carbonic anhydrase inhibitors. These inhibitors are applied in the treatment of glaucoma, epilepsy, and certain types of edema. The sulfonamide group enhances binding to the carbonic anhydrase enzyme, while the chloro and methyl substitutions improve metabolic stability and selectivity. Its lipophilic character aids in membrane penetration, making it suitable for drugs requiring central nervous system access. Also explored in antimicrobial and anticancer research due to its ability to modulate enzyme activity in pathological cells.
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