2-Chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one

97%

  • Product Code: 163739
  CAS:    1013916-37-4
Molecular Weight: 263.72 g./mol Molecular Formula: C₁₃H₁₄ClN₃O
EC Number: MDL Number: MFCD13181207
Melting Point: Boiling Point: 428.0±34.0 °C at 760 mmHg
Density: Storage Condition: Room temperature, inert gas
Product Description: Used as a key intermediate in the synthesis of cyclin-dependent kinase (CDK) inhibitors, particularly in the development of anticancer agents. Its structure allows selective binding to CDK enzymes, making it valuable in targeted cancer therapies. It has been studied in the context of inhibiting CDK2 and CDK4, which play critical roles in cell cycle regulation. Due to its ability to cross cell membranes and exhibit good metabolic stability, it is favored in medicinal chemistry for optimizing drug candidates aimed at treating solid tumors and hematological malignancies.
Sizes / Availability / Pricing:
Size Availability Price Quantity
25.000 10-20 days ฿2,530.00
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5.000 10-20 days ฿670.00
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2-Chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one
Used as a key intermediate in the synthesis of cyclin-dependent kinase (CDK) inhibitors, particularly in the development of anticancer agents. Its structure allows selective binding to CDK enzymes, making it valuable in targeted cancer therapies. It has been studied in the context of inhibiting CDK2 and CDK4, which play critical roles in cell cycle regulation. Due to its ability to cross cell membranes and exhibit good metabolic stability, it is favored in medicinal chemistry for optimizing drug candidates aimed at treating solid tumors and hematological malignancies.
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