2-(3-Chloro-4-ethoxy-5-fluorophenyl)-4, 4, 5, 5-tetramethyl-1, 3, 2-dioxaborolane

95%

  • Product Code: 164043
  CAS:    1668474-08-5
Molecular Weight: 300.56 g./mol Molecular Formula: C₁₄H₁₉BClFO₃
EC Number: MDL Number: MFCD24368960
Melting Point: Boiling Point:
Density: Storage Condition: Room temperature, dry
Product Description: Used primarily as a key intermediate in pharmaceutical synthesis, especially in Suzuki-Miyaura cross-coupling reactions to form carbon-carbon bonds. Its boronate ester group enables efficient coupling with aryl halides, making it valuable in constructing complex aromatic systems found in bioactive molecules. Commonly applied in the development of fluorinated and chlorinated drug candidates, where precise substitution patterns are critical for biological activity. Its ethoxy and fluoro substituents contribute to improved metabolic stability and target binding in medicinal chemistry applications.
Sizes / Availability / Pricing:
Size Availability Price Quantity
100mg 10-20 days ฿1,950.00
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1g 10-20 days ฿8,950.00
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5g 10-20 days ฿31,330.00
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-
250mg 10-20 days ฿3,320.00
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2-(3-Chloro-4-ethoxy-5-fluorophenyl)-4, 4, 5, 5-tetramethyl-1, 3, 2-dioxaborolane
Used primarily as a key intermediate in pharmaceutical synthesis, especially in Suzuki-Miyaura cross-coupling reactions to form carbon-carbon bonds. Its boronate ester group enables efficient coupling with aryl halides, making it valuable in constructing complex aromatic systems found in bioactive molecules. Commonly applied in the development of fluorinated and chlorinated drug candidates, where precise substitution patterns are critical for biological activity. Its ethoxy and fluoro substituents contribute to improved metabolic stability and target binding in medicinal chemistry applications.
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