1-(2-Chloro-4-((6-cyano-7-methoxyquinolin-4-yl)oxy)phenyl)-3-cyclopropylurea

95%

  • Product Code: 164861
  CAS:    1882873-21-3
Molecular Weight: 408.84 g./mol Molecular Formula: C₂₁H₁₇ClN₄O₃
EC Number: MDL Number:
Melting Point: Boiling Point:
Density: Storage Condition: 2-8°C, dry
Product Description: Used as a key intermediate in the synthesis of tyrosine kinase inhibitors, particularly in targeted cancer therapies. It plays a role in blocking signaling pathways that promote tumor growth, especially in non-small cell lung cancer and other solid tumors. Its structure allows for strong binding to mutant forms of EGFR, making it valuable in developing drugs resistant to first-generation inhibitors. Also utilized in research for optimizing selectivity and reducing off-target effects in kinase inhibitor design.
Sizes / Availability / Pricing:
Size Availability Price Quantity
0.250 G 10-20 days ฿24,120.00
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1.000 G 10-20 days ฿77,840.00
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-
0.100 G 10-20 days ฿14,550.00
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1-(2-Chloro-4-((6-cyano-7-methoxyquinolin-4-yl)oxy)phenyl)-3-cyclopropylurea
Used as a key intermediate in the synthesis of tyrosine kinase inhibitors, particularly in targeted cancer therapies. It plays a role in blocking signaling pathways that promote tumor growth, especially in non-small cell lung cancer and other solid tumors. Its structure allows for strong binding to mutant forms of EGFR, making it valuable in developing drugs resistant to first-generation inhibitors. Also utilized in research for optimizing selectivity and reducing off-target effects in kinase inhibitor design.
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