1-(2-Chloro-4-((6-cyano-7-methoxyquinolin-4-yl)oxy)phenyl)-3-cyclopropylurea
95%
- Product Code: 164861
CAS:
1882873-21-3
Molecular Weight: | 408.84 g./mol | Molecular Formula: | C₂₁H₁₇ClN₄O₃ |
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Density: | Storage Condition: | 2-8°C, dry |
Product Description:
Used as a key intermediate in the synthesis of tyrosine kinase inhibitors, particularly in targeted cancer therapies. It plays a role in blocking signaling pathways that promote tumor growth, especially in non-small cell lung cancer and other solid tumors. Its structure allows for strong binding to mutant forms of EGFR, making it valuable in developing drugs resistant to first-generation inhibitors. Also utilized in research for optimizing selectivity and reducing off-target effects in kinase inhibitor design.
Sizes / Availability / Pricing:
Size | Availability | Price | Quantity |
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0.250 G | 10-20 days | ฿24,120.00 |
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1.000 G | 10-20 days | ฿77,840.00 |
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0.100 G | 10-20 days | ฿14,550.00 |
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1-(2-Chloro-4-((6-cyano-7-methoxyquinolin-4-yl)oxy)phenyl)-3-cyclopropylurea
Used as a key intermediate in the synthesis of tyrosine kinase inhibitors, particularly in targeted cancer therapies. It plays a role in blocking signaling pathways that promote tumor growth, especially in non-small cell lung cancer and other solid tumors. Its structure allows for strong binding to mutant forms of EGFR, making it valuable in developing drugs resistant to first-generation inhibitors. Also utilized in research for optimizing selectivity and reducing off-target effects in kinase inhibitor design.
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