3-Chlorobicyclo[1.1.1]pentan-1-amine hydrochloride

95%

  • Product Code: 164862
  CAS:    1886967-25-4
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Density: Storage Condition: 2-8°C, Inert Gas
Product Description: Used as a key building block in medicinal chemistry, particularly in the development of bioactive molecules and pharmaceuticals. Its rigid bicyclic structure acts as a high-strain linker that can improve metabolic stability, membrane permeability, and target binding selectivity. Commonly employed in the synthesis of novel drug candidates, especially as a bioisostere for phenyl or tert-butyl groups to modulate physicochemical properties. Frequently utilized in fragment-based drug discovery and in the design of CNS-targeted compounds due to its favorable polarity and three-dimensional character. Also applied in the preparation of covalent inhibitors and PROTACs where spatial control and stability are critical.
Sizes / Availability / Pricing:
Size Availability Price Quantity
0.100 G 10-20 days ฿17,780.00
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0.250 G 10-20 days ฿28,930.00
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3-Chlorobicyclo[1.1.1]pentan-1-amine hydrochloride
Used as a key building block in medicinal chemistry, particularly in the development of bioactive molecules and pharmaceuticals. Its rigid bicyclic structure acts as a high-strain linker that can improve metabolic stability, membrane permeability, and target binding selectivity. Commonly employed in the synthesis of novel drug candidates, especially as a bioisostere for phenyl or tert-butyl groups to modulate physicochemical properties. Frequently utilized in fragment-based drug discovery and in the design of CNS-targeted compounds due to its favorable polarity and three-dimensional character. Also applied in the preparation of covalent inhibitors and PROTACs where spatial control and stability are critical.
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