7-Chloro-4-(4-(pyrimidin-2-yl)piperazin-1-yl)quinoline
98%
- Product Code: 165123
CAS:
643042-43-7
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| Density: | Storage Condition: | 2-8°C, light-proof, inert gas |
Product Description:
Used as a key intermediate in the synthesis of antimalarial drugs, particularly in the development of quinoline-based derivatives that target drug-resistant strains of Plasmodium falciparum. Its structure enables enhanced binding to heme molecules in the parasite, disrupting detoxification processes. Also investigated for its potential in central nervous system agents due to the piperazine-pyrimidine moiety, which shows affinity for serotonin and dopamine receptors. Employed in medicinal chemistry research to optimize pharmacokinetic properties in new drug candidates.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 25mg | 10-20 days | ฿37,360.00 |
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| 50mg | 10-20 days | ฿67,250.00 |
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7-Chloro-4-(4-(pyrimidin-2-yl)piperazin-1-yl)quinoline
Used as a key intermediate in the synthesis of antimalarial drugs, particularly in the development of quinoline-based derivatives that target drug-resistant strains of Plasmodium falciparum. Its structure enables enhanced binding to heme molecules in the parasite, disrupting detoxification processes. Also investigated for its potential in central nervous system agents due to the piperazine-pyrimidine moiety, which shows affinity for serotonin and dopamine receptors. Employed in medicinal chemistry research to optimize pharmacokinetic properties in new drug candidates.
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