trans-3-(Cyanomethyl)-3-(4-(6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl)-1H-pyrazol-1-yl)cyclobutanecarbonitrile
98%
- Product Code: 165866
CAS:
2127109-84-4
| Molecular Weight: | 383.41 g./mol | Molecular Formula: | C₂₀H₁₇N₉ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD32197240 | |
| Melting Point: | Boiling Point: | ||
| Density: | 1.46±0.1 g/cm3(Predicted) | Storage Condition: | 2-8°C, sealed, dry |
Product Description:
Used in pharmaceutical research as a potent and selective inhibitor of Janus kinase 2 (JAK2), particularly in the development of treatments for myeloproliferative disorders. Shows promising activity in suppressing abnormal cell signaling associated with JAK2 mutations, such as V617F. Investigated for its potential in treating conditions like polycythemia vera and myelofibrosis due to its ability to modulate inflammatory and proliferative pathways. Also employed as a chemical probe to study JAK-STAT signaling in cellular models.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 5mg | 10-20 days | ฿11,520.00 |
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| 10mg | 10-20 days | ฿21,680.00 |
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| 25mg | 10-20 days | ฿45,350.00 |
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| 50mg | 10-20 days | ฿70,730.00 |
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trans-3-(Cyanomethyl)-3-(4-(6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl)-1H-pyrazol-1-yl)cyclobutanecarbonitrile
Used in pharmaceutical research as a potent and selective inhibitor of Janus kinase 2 (JAK2), particularly in the development of treatments for myeloproliferative disorders. Shows promising activity in suppressing abnormal cell signaling associated with JAK2 mutations, such as V617F. Investigated for its potential in treating conditions like polycythemia vera and myelofibrosis due to its ability to modulate inflammatory and proliferative pathways. Also employed as a chemical probe to study JAK-STAT signaling in cellular models.
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