2-Chloro-5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-amine
98%
- Product Code: 166306
CAS:
1375301-51-1
Molecular Weight: | 182.61 g./mol | Molecular Formula: | C₇H₇ClN₄ |
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Density: | Storage Condition: | 2-8°C |
Product Description:
Used as a key intermediate in the synthesis of kinase inhibitors, particularly in the development of anticancer agents. Its structure allows selective binding to ATP sites in protein kinases, making it valuable in targeted therapies for cancers such as leukemia and non-small cell lung carcinoma. Also employed in the preparation of JAK2 and FLT3 inhibitors, where it contributes to modulating signal transduction pathways involved in cell proliferation and survival. Its chloro and amino groups provide reactive handles for further functionalization in medicinal chemistry campaigns.
Sizes / Availability / Pricing:
Size | Availability | Price | Quantity |
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100mg | 10-20 days | ฿13,410.00 |
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2-Chloro-5-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-amine
Used as a key intermediate in the synthesis of kinase inhibitors, particularly in the development of anticancer agents. Its structure allows selective binding to ATP sites in protein kinases, making it valuable in targeted therapies for cancers such as leukemia and non-small cell lung carcinoma. Also employed in the preparation of JAK2 and FLT3 inhibitors, where it contributes to modulating signal transduction pathways involved in cell proliferation and survival. Its chloro and amino groups provide reactive handles for further functionalization in medicinal chemistry campaigns.
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