3-Cyano-N-(3-(1-Isobutyrylpiperidin-4-Yl)-1-Methyl-4-(Trifluoromethyl)-1H-Pyrrolo[2,3-B]Pyridin-5-Yl)Benzamide
98%
- Product Code: 166877
CAS:
1892576-58-7
| Molecular Weight: | 497.51 g./mol | Molecular Formula: | C₂₆H₂₆F₃N₅O₂ |
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| EC Number: | MDL Number: | ||
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| Density: | Storage Condition: | 2-8°C |
Product Description:
Used in pharmaceutical research as a potent and selective inhibitor of Janus kinase 2 (JAK2), particularly in the development of treatments for autoimmune diseases and inflammatory conditions. It modulates cytokine signaling pathways involved in immune response, showing potential in models of rheumatoid arthritis, psoriasis, and other chronic inflammatory disorders. Due to its ability to cross the blood-brain barrier, it is also investigated for neuroinflammatory diseases. Its structure allows for high target specificity, reducing off-target effects in cellular assays. Currently utilized primarily as a preclinical tool compound for validating JAK2-dependent pathways in disease models.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.050 G | 10-20 days | ฿35,920.00 |
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| 0.100 G | 10-20 days | ฿61,060.00 |
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| 0.250 G | 10-20 days | ฿112,410.00 |
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| 0.025 G | 10-20 days | ฿21,130.00 |
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3-Cyano-N-(3-(1-Isobutyrylpiperidin-4-Yl)-1-Methyl-4-(Trifluoromethyl)-1H-Pyrrolo[2,3-B]Pyridin-5-Yl)Benzamide
Used in pharmaceutical research as a potent and selective inhibitor of Janus kinase 2 (JAK2), particularly in the development of treatments for autoimmune diseases and inflammatory conditions. It modulates cytokine signaling pathways involved in immune response, showing potential in models of rheumatoid arthritis, psoriasis, and other chronic inflammatory disorders. Due to its ability to cross the blood-brain barrier, it is also investigated for neuroinflammatory diseases. Its structure allows for high target specificity, reducing off-target effects in cellular assays. Currently utilized primarily as a preclinical tool compound for validating JAK2-dependent pathways in disease models.
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