3-(4,5-difluoro-1-oxoisoindolin-2-yl)piperidine-2,6-dione
98%
- Product Code: 167097
CAS:
2839672-68-1
| Molecular Weight: | 280.23 g./mol | Molecular Formula: | C₁₃H₁₀F₂N₂O₃ |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C |
Product Description:
Used as a key intermediate in the synthesis of immunomodulatory drugs, particularly in the development of cereblon E3 ligase modulators. It plays a critical role in targeted protein degradation therapies, including treatments for certain cancers such as multiple myeloma and myelodysplastic syndromes. Its structure enables selective binding to cereblon, facilitating the degradation of disease-causing proteins. Also employed in research for developing novel therapeutics in oncology and inflammatory diseases.
Product Specification:
| Test | Specification |
|---|---|
| Appearance | Grey Solid |
| Purity | 97.5-100% |
| Infrared Spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 G | 10-20 days | ฿5,960.00 |
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| 0.025 G | 10-20 days | ฿17,860.00 |
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| 0.100 G | 10-20 days | ฿53,600.00 |
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3-(4,5-difluoro-1-oxoisoindolin-2-yl)piperidine-2,6-dione
Used as a key intermediate in the synthesis of immunomodulatory drugs, particularly in the development of cereblon E3 ligase modulators. It plays a critical role in targeted protein degradation therapies, including treatments for certain cancers such as multiple myeloma and myelodysplastic syndromes. Its structure enables selective binding to cereblon, facilitating the degradation of disease-causing proteins. Also employed in research for developing novel therapeutics in oncology and inflammatory diseases.
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| Appearance | - |
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| Mix Method | - |
| Heat Resistance | - |
| Stable in pH range | - |
| Solubility | - |
| Product Types | - |
| INCI | - |
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