Diethyl ((2-bromo-4-methylphenyl)difluoromethyl)phosphonate
98%
- Product Code: 167366
CAS:
863977-42-8
Molecular Weight: | 357.13 g./mol | Molecular Formula: | C₁₂H₁₆BrF₂O₃P |
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EC Number: | MDL Number: | ||
Melting Point: | Boiling Point: | 373.2±42.0 °C(Predicted) | |
Density: | 1.412±0.06 g/cm3(Predicted) | Storage Condition: | 2-8°C, sealed, dry, light-proof |
Product Description:
Used as a key intermediate in the synthesis of fluorinated pharmaceuticals and agrochemicals due to its ability to introduce difluoromethylphosphonate groups into organic molecules. Its bromo and methyl substituents allow for further functionalization through cross-coupling reactions, making it valuable in medicinal chemistry for developing bioactive compounds. Commonly employed in the preparation of enzyme inhibitors and kinase-targeted agents, where the phosphonate moiety mimics phosphate esters in biological systems. Also utilized in the development of novel pesticides, leveraging the stability and reactivity of the difluoromethyl group to enhance metabolic resistance and target specificity.
Sizes / Availability / Pricing:
Size | Availability | Price | Quantity |
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100mg | 10-20 days | ฿16,670.00 |
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250mg | 10-20 days | ฿28,310.00 |
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1g | 10-20 days | ฿79,300.00 |
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Diethyl ((2-bromo-4-methylphenyl)difluoromethyl)phosphonate
Used as a key intermediate in the synthesis of fluorinated pharmaceuticals and agrochemicals due to its ability to introduce difluoromethylphosphonate groups into organic molecules. Its bromo and methyl substituents allow for further functionalization through cross-coupling reactions, making it valuable in medicinal chemistry for developing bioactive compounds. Commonly employed in the preparation of enzyme inhibitors and kinase-targeted agents, where the phosphonate moiety mimics phosphate esters in biological systems. Also utilized in the development of novel pesticides, leveraging the stability and reactivity of the difluoromethyl group to enhance metabolic resistance and target specificity.
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