Diethyl ((2-bromo-4-methylphenyl)difluoromethyl)phosphonate

98%

  • Product Code: 167366
  CAS:    863977-42-8
Molecular Weight: 357.13 g./mol Molecular Formula: C₁₂H₁₆BrF₂O₃P
EC Number: MDL Number:
Melting Point: Boiling Point: 373.2±42.0 °C(Predicted)
Density: 1.412±0.06 g/cm3(Predicted) Storage Condition: 2-8°C, sealed, dry, light-proof
Product Description: Used as a key intermediate in the synthesis of fluorinated pharmaceuticals and agrochemicals due to its ability to introduce difluoromethylphosphonate groups into organic molecules. Its bromo and methyl substituents allow for further functionalization through cross-coupling reactions, making it valuable in medicinal chemistry for developing bioactive compounds. Commonly employed in the preparation of enzyme inhibitors and kinase-targeted agents, where the phosphonate moiety mimics phosphate esters in biological systems. Also utilized in the development of novel pesticides, leveraging the stability and reactivity of the difluoromethyl group to enhance metabolic resistance and target specificity.
Sizes / Availability / Pricing:
Size Availability Price Quantity
100mg 10-20 days ฿16,670.00
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250mg 10-20 days ฿28,310.00
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-
1g 10-20 days ฿79,300.00
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Diethyl ((2-bromo-4-methylphenyl)difluoromethyl)phosphonate
Used as a key intermediate in the synthesis of fluorinated pharmaceuticals and agrochemicals due to its ability to introduce difluoromethylphosphonate groups into organic molecules. Its bromo and methyl substituents allow for further functionalization through cross-coupling reactions, making it valuable in medicinal chemistry for developing bioactive compounds. Commonly employed in the preparation of enzyme inhibitors and kinase-targeted agents, where the phosphonate moiety mimics phosphate esters in biological systems. Also utilized in the development of novel pesticides, leveraging the stability and reactivity of the difluoromethyl group to enhance metabolic resistance and target specificity.
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