(Difluoro(phenylthio)methyl)trimethylsilane
97%
- Product Code: 167465
CAS:
536975-49-2
| Molecular Weight: | 232.37 g./mol | Molecular Formula: | C₁₀H₁₄F₂SSi |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD19442557 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C, Inert Gas |
Product Description:
Used as a fluorinating reagent in organic synthesis, particularly in the introduction of difluoromethylthio groups into bioactive molecules. Its silicon-containing structure enhances reactivity and selectivity in electrophilic fluorination reactions. Commonly applied in medicinal chemistry for the development of fluorinated pharmaceuticals, where the difluoro(phenylthio)methyl group acts as a lipophilic hydrogen-bond acceptor, improving metabolic stability and membrane permeability. Also employed in agrochemical synthesis to modify pesticide and herbicide candidates for improved efficacy and environmental persistence. The reagent’s stability and ease of handling make it suitable for late-stage functionalization in complex molecule synthesis.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 100mg | 10-20 days | $686.64 |
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| 250mg | 10-20 days | $1,373.67 |
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| 50mg | 10-20 days | $403.72 |
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(Difluoro(phenylthio)methyl)trimethylsilane
Used as a fluorinating reagent in organic synthesis, particularly in the introduction of difluoromethylthio groups into bioactive molecules. Its silicon-containing structure enhances reactivity and selectivity in electrophilic fluorination reactions. Commonly applied in medicinal chemistry for the development of fluorinated pharmaceuticals, where the difluoro(phenylthio)methyl group acts as a lipophilic hydrogen-bond acceptor, improving metabolic stability and membrane permeability. Also employed in agrochemical synthesis to modify pesticide and herbicide candidates for improved efficacy and environmental persistence. The reagent’s stability and ease of handling make it suitable for late-stage functionalization in complex molecule synthesis.
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