1-Boc-3-bromo-6-fluoroindole
≥97%
- Product Code: 173637
CAS:
1314406-46-6
| Molecular Weight: | 314.15 g./mol | Molecular Formula: | C₁₃H₁₃BrFNO₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD19442769 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | Room temperature, dry |
Product Description:
Used as a key intermediate in the synthesis of biologically active indole derivatives, particularly in pharmaceutical research. The Boc-protected amine and bromo substituent allow for selective functionalization, making it valuable in constructing complex molecules such as serotonin receptor modulators or kinase inhibitors. The presence of the bromine atom enables cross-coupling reactions like Suzuki or Heck reactions, facilitating the introduction of aryl or alkenyl groups. Its fluoro substitution enhances binding affinity in target molecules, often improving metabolic stability and bioavailability in drug candidates. Commonly employed in medicinal chemistry for developing central nervous system agents and anticancer compounds.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 250mg | 10-20 days | ฿2,370.00 |
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| 1g | 10-20 days | ฿7,970.00 |
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1-Boc-3-bromo-6-fluoroindole
Used as a key intermediate in the synthesis of biologically active indole derivatives, particularly in pharmaceutical research. The Boc-protected amine and bromo substituent allow for selective functionalization, making it valuable in constructing complex molecules such as serotonin receptor modulators or kinase inhibitors. The presence of the bromine atom enables cross-coupling reactions like Suzuki or Heck reactions, facilitating the introduction of aryl or alkenyl groups. Its fluoro substitution enhances binding affinity in target molecules, often improving metabolic stability and bioavailability in drug candidates. Commonly employed in medicinal chemistry for developing central nervous system agents and anticancer compounds.
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