1-Boc-3-bromo-5-nitro-1H-indazole
95%
- Product Code: 173680
CAS:
473416-22-7
| Molecular Weight: | 342.15 g./mol | Molecular Formula: | C₁₂H₁₂BrN₃O₄ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD11617131 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | Room temperature, dry |
Product Description:
Used as a key intermediate in the synthesis of biologically active indazole derivatives, particularly in pharmaceutical research. The Boc-protected indazole scaffold allows for selective functionalization at the bromo and nitro positions, enabling sequential cross-coupling reactions such as Suzuki or Buchwald–Hartwig aminations. Commonly employed in the development of kinase inhibitors and other medicinal agents targeting cancer and inflammatory diseases. The nitro group can be reduced to an amine for further derivatization, expanding its utility in library synthesis for drug discovery. Stable under standard handling conditions, it is suitable for use in multi-step synthetic routes requiring selective deprotection and coupling strategies.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1g | 10-20 days | ฿8,160.00 |
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| 5g | 10-20 days | ฿18,510.00 |
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1-Boc-3-bromo-5-nitro-1H-indazole
Used as a key intermediate in the synthesis of biologically active indazole derivatives, particularly in pharmaceutical research. The Boc-protected indazole scaffold allows for selective functionalization at the bromo and nitro positions, enabling sequential cross-coupling reactions such as Suzuki or Buchwald–Hartwig aminations. Commonly employed in the development of kinase inhibitors and other medicinal agents targeting cancer and inflammatory diseases. The nitro group can be reduced to an amine for further derivatization, expanding its utility in library synthesis for drug discovery. Stable under standard handling conditions, it is suitable for use in multi-step synthetic routes requiring selective deprotection and coupling strategies.
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