(2,4-Difluoro-3-formylphenyl)boronic acid
95%
- Product Code: 176571
CAS:
870718-06-2
| Molecular Weight: | 185.92 g./mol | Molecular Formula: | F₂C₆H₂(CHO)B(OH)₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD04974116 | |
| Melting Point: | 206 - 210 ℃ - lit. | Boiling Point: | 332.5 ℃ at 760 mmHg |
| Density: | 1.42±0.1 g/cm3(Predicted) | Storage Condition: | 2-8°C |
Product Description:
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. Its aldehyde and boronic acid functional groups allow for versatile coupling reactions, such as Suzuki-Miyaura cross-coupling and imine formation, enabling the construction of complex drug-like molecules. Commonly employed in medicinal chemistry for lead optimization due to its ability to enhance binding affinity and metabolic stability in target molecules. Also utilized in the preparation of fluorescent probes and sensors owing to its reactivity with nucleophiles and ability to coordinate with diols in saccharide detection.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 250mg | 10-20 days | ฿370.00 |
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| 1g | 10-20 days | ฿1,150.00 |
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| 5g | 10-20 days | ฿2,262.00 |
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(2,4-Difluoro-3-formylphenyl)boronic acid
Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. Its aldehyde and boronic acid functional groups allow for versatile coupling reactions, such as Suzuki-Miyaura cross-coupling and imine formation, enabling the construction of complex drug-like molecules. Commonly employed in medicinal chemistry for lead optimization due to its ability to enhance binding affinity and metabolic stability in target molecules. Also utilized in the preparation of fluorescent probes and sensors owing to its reactivity with nucleophiles and ability to coordinate with diols in saccharide detection.
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