2-(4-(((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)pentanedioic acid
98%
- Product Code: 176772
CAS:
60388-53-6
| Molecular Weight: | 454.44 g./mol | Molecular Formula: | C₂₀H₂₂N₈O₆ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00064369 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C, dry, avoid light |
Product Description:
Used primarily as a folate antagonist in medical research and cancer treatment, this compound functions as a potent inhibitor of dihydrofolate reductase (DHFR), an enzyme critical for DNA synthesis and cell division. It is employed in the study of antifolate resistance mechanisms and serves as a key intermediate in the development of targeted chemotherapeutic agents. Its structure allows for selective activity against rapidly dividing cells, making it valuable in oncology research, particularly in the design of drug conjugates for tumor-specific delivery. Additionally, it has been explored in autoimmune disease research due to its immunomodulatory effects.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.005 | 10-20 days | ฿40,470.00 |
+
-
|
2-(4-(((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)pentanedioic acid
Used primarily as a folate antagonist in medical research and cancer treatment, this compound functions as a potent inhibitor of dihydrofolate reductase (DHFR), an enzyme critical for DNA synthesis and cell division. It is employed in the study of antifolate resistance mechanisms and serves as a key intermediate in the development of targeted chemotherapeutic agents. Its structure allows for selective activity against rapidly dividing cells, making it valuable in oncology research, particularly in the design of drug conjugates for tumor-specific delivery. Additionally, it has been explored in autoimmune disease research due to its immunomodulatory effects.
| Mechanism | - |
| Appearance | - |
| Longevity | - |
| Strength | - |
| Storage | - |
| Shelf Life | - |
| Allergen(s) | - |
| Dosage (Range) | - |
| Recommended Dosage | - |
| Dosage (Per Day) | - |
| Recommended Dosage (Per Day) | - |
| Mix Method | - |
| Heat Resistance | - |
| Stable in pH range | - |
| Solubility | - |
| Product Types | - |
| INCI | - |
Purchase History for
Loading purchase history...
Cart
No products
Subtotal:
฿0.00
฿0.00
Total :