[2-(Difluoromethyl)phenyl]methanol, 2-(Hydroxymethyl)benzal fluoride

98%

  • Product Code: 177558
  CAS:    1018678-49-3
Molecular Weight: 158.15 g./mol Molecular Formula: C₈H₈F₂O
EC Number: MDL Number: MFCD26728124
Melting Point: Boiling Point:
Density: Storage Condition: Room temperature
Product Description: Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of fluorinated active pharmaceutical ingredients (APIs) where the difluoromethyl group enhances metabolic stability and bioavailability. Its structure allows for selective derivatization, making it valuable in medicinal chemistry for creating analogs with improved pharmacokinetic profiles. Also employed in agrochemical research for designing novel pesticides and herbicides, leveraging the fluorine atoms to increase lipophilicity and membrane permeability. Commonly utilized in late-stage functionalization due to the reactivity of the hydroxymethyl group, enabling efficient coupling reactions in drug discovery.
Sizes / Availability / Pricing:
Size Availability Price Quantity
250mg 10-20 days ฿9,680.00
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-
1g 10-20 days ฿21,500.00
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-
[2-(Difluoromethyl)phenyl]methanol, 2-(Hydroxymethyl)benzal fluoride
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of fluorinated active pharmaceutical ingredients (APIs) where the difluoromethyl group enhances metabolic stability and bioavailability. Its structure allows for selective derivatization, making it valuable in medicinal chemistry for creating analogs with improved pharmacokinetic profiles. Also employed in agrochemical research for designing novel pesticides and herbicides, leveraging the fluorine atoms to increase lipophilicity and membrane permeability. Commonly utilized in late-stage functionalization due to the reactivity of the hydroxymethyl group, enabling efficient coupling reactions in drug discovery.
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