4, 5-Dimethyl-2-(trimethylsilyl)phenyl trifluoromethanesulfonate

97%

  • Product Code: 178041
  CAS:    458566-99-9
Molecular Weight: 326.41 g./mol Molecular Formula: C₁₂H₁₇F₃O₃SSi
EC Number: MDL Number: MFCD28969391
Melting Point: Boiling Point:
Density: Storage Condition: Room temperature, seal, dry, light-proof
Product Description: Used as a key reagent in organic synthesis, particularly in palladium-catalyzed cross-coupling reactions such as Suzuki-Miyaura and Stille couplings. Its triflate group acts as an excellent leaving group, enabling efficient formation of carbon-carbon bonds. The trimethylsilyl and dimethyl substituents provide steric and electronic stabilization to intermediates, enhancing selectivity and yield in complex molecule construction. Commonly employed in the synthesis of pharmaceuticals, agrochemicals, and advanced materials where precise molecular architecture is required. Stable under a range of reaction conditions, it allows for sequential transformations in multi-step synthetic routes.
Sizes / Availability / Pricing:
Size Availability Price Quantity
100mg 10-20 days £86.55
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250mg 10-20 days £119.06
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5g 10-20 days £1,100.43
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1g 10-20 days £320.56
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4, 5-Dimethyl-2-(trimethylsilyl)phenyl trifluoromethanesulfonate
Used as a key reagent in organic synthesis, particularly in palladium-catalyzed cross-coupling reactions such as Suzuki-Miyaura and Stille couplings. Its triflate group acts as an excellent leaving group, enabling efficient formation of carbon-carbon bonds. The trimethylsilyl and dimethyl substituents provide steric and electronic stabilization to intermediates, enhancing selectivity and yield in complex molecule construction. Commonly employed in the synthesis of pharmaceuticals, agrochemicals, and advanced materials where precise molecular architecture is required. Stable under a range of reaction conditions, it allows for sequential transformations in multi-step synthetic routes.
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