Di-tert-butyl(methyl)silane
97%
- Product Code: 178052
CAS:
56310-20-4
| Molecular Weight: | 158.36 g./mol | Molecular Formula: | C₉H₂₂Si |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00054890 | |
| Melting Point: | Boiling Point: | 155 °C | |
| Density: | 0.758 g/cm3 | Storage Condition: | Room temperature, inert gas |
Product Description:
Used as a silyl protecting group in organic synthesis, particularly for alcohols and phenols. The di-tert-butylmethylsilyl (DTBMS) group offers high stability under a variety of reaction conditions, including basic and mildly acidic environments, making it suitable for multi-step syntheses. It is more sterically hindered and more stable toward hydrolysis than smaller silyl groups like TMS or TBS, allowing selective deprotection in the presence of other silyl-protected functionalities. Commonly employed in the synthesis of complex natural products and pharmaceuticals where robust protection is required.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 25g | 10-20 days | ฿86,980.00 |
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Di-tert-butyl(methyl)silane
Used as a silyl protecting group in organic synthesis, particularly for alcohols and phenols. The di-tert-butylmethylsilyl (DTBMS) group offers high stability under a variety of reaction conditions, including basic and mildly acidic environments, making it suitable for multi-step syntheses. It is more sterically hindered and more stable toward hydrolysis than smaller silyl groups like TMS or TBS, allowing selective deprotection in the presence of other silyl-protected functionalities. Commonly employed in the synthesis of complex natural products and pharmaceuticals where robust protection is required.
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