2-(4,5-Difluoro-2-methoxyphenyl)acetonitrile

98%

  • Product Code: 178792
  CAS:    886761-74-6
Molecular Weight: 183.16 g./mol Molecular Formula: C₉H₇F₂NO
EC Number: MDL Number: MFCD06660349
Melting Point: Boiling Point:
Density: Storage Condition: 2-8°C, dry
Product Description: Used as a key intermediate in the synthesis of fluorinated pharmaceuticals, particularly in the development of selective serotonin reuptake inhibitors (SSRIs) and other central nervous system agents. Its difluoro-methoxy aromatic structure enhances metabolic stability and membrane permeability, making it valuable in optimizing drug candidates for improved bioavailability and target binding. Commonly employed in late-stage functionalization during medicinal chemistry campaigns to introduce fluorinated motifs that modulate lipophilicity and pharmacokinetic profiles.
Sizes / Availability / Pricing:
Size Availability Price Quantity
100mg 10-20 days ฿840.00
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-
250mg 10-20 days ฿1,850.00
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-
1g 10-20 days ฿6,180.00
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-
2-(4,5-Difluoro-2-methoxyphenyl)acetonitrile
Used as a key intermediate in the synthesis of fluorinated pharmaceuticals, particularly in the development of selective serotonin reuptake inhibitors (SSRIs) and other central nervous system agents. Its difluoro-methoxy aromatic structure enhances metabolic stability and membrane permeability, making it valuable in optimizing drug candidates for improved bioavailability and target binding. Commonly employed in late-stage functionalization during medicinal chemistry campaigns to introduce fluorinated motifs that modulate lipophilicity and pharmacokinetic profiles.
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