2-(2,6-Dioxopiperidin-3-yl)phthalimidine 5-fluoride
98%
- Product Code: 179091
CAS:
2468780-76-7
| Molecular Weight: | 262.24 g./mol | Molecular Formula: | C₁₃H₁₁FN₂O₃ |
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| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | Room temperature, dry |
Product Description:
Used primarily in pharmaceutical research, this compound serves as a key intermediate in the synthesis of immunomodulatory drugs. It is notably involved in the development of analogs related to thalidomide, designed to enhance anti-inflammatory, antitumor, and cereblon-binding activities. Its fluorinated structure improves metabolic stability and bioavailability, making it valuable in oncology drug discovery, especially for hematological cancers such as multiple myeloma. Additionally, it supports structure-activity relationship (SAR) studies to optimize potency and reduce off-target effects in new therapeutic agents.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 100mg | 10-20 days | ฿2,880.00 |
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| 250mg | 10-20 days | ฿5,080.00 |
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| 500mg | 10-20 days | ฿8,630.00 |
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| 1g | 10-20 days | ฿10,900.00 |
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| 5g | 10-20 days | ฿38,200.00 |
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| 10g | 10-20 days | ฿74,670.00 |
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| bulk | 10-20 days | ฿0.00 |
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2-(2,6-Dioxopiperidin-3-yl)phthalimidine 5-fluoride
Used primarily in pharmaceutical research, this compound serves as a key intermediate in the synthesis of immunomodulatory drugs. It is notably involved in the development of analogs related to thalidomide, designed to enhance anti-inflammatory, antitumor, and cereblon-binding activities. Its fluorinated structure improves metabolic stability and bioavailability, making it valuable in oncology drug discovery, especially for hematological cancers such as multiple myeloma. Additionally, it supports structure-activity relationship (SAR) studies to optimize potency and reduce off-target effects in new therapeutic agents.
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| Stable in pH range | - |
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