2-(2,6-Dioxopiperidin-3-yl)-5-(prop-2-yn-1-yloxy)isoindoline-1,3-dione
98%
- Product Code: 179481
CAS:
2226303-74-6
| Molecular Weight: | 312.28 g./mol | Molecular Formula: | C₁₆H₁₂N₂O₅ |
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| Density: | Storage Condition: | 2-8°C |
Product Description:
Used primarily in pharmaceutical research, this compound serves as a key intermediate in the synthesis of targeted protein degraders, particularly cereblon E3 ligase modulators. It plays a critical role in the development of PROTACs (proteolysis-targeting chimeras), which are bifunctional molecules designed to induce the degradation of disease-causing proteins. Its alkyne functional group allows for efficient conjugation via click chemistry, enabling rapid assembly of complex drug candidates. Due to its ability to engage cereblon, it is widely utilized in oncology and immunology drug discovery programs, especially in the creation of novel anticancer agents with improved selectivity and potency.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 50mg | 10-20 days | ฿11,400.00 |
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2-(2,6-Dioxopiperidin-3-yl)-5-(prop-2-yn-1-yloxy)isoindoline-1,3-dione
Used primarily in pharmaceutical research, this compound serves as a key intermediate in the synthesis of targeted protein degraders, particularly cereblon E3 ligase modulators. It plays a critical role in the development of PROTACs (proteolysis-targeting chimeras), which are bifunctional molecules designed to induce the degradation of disease-causing proteins. Its alkyne functional group allows for efficient conjugation via click chemistry, enabling rapid assembly of complex drug candidates. Due to its ability to engage cereblon, it is widely utilized in oncology and immunology drug discovery programs, especially in the creation of novel anticancer agents with improved selectivity and potency.
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