4-(1-(2,4-Diaminopteridin-6-yl)pent-4-yn-2-yl)benzoicacid
97%
- Product Code: 179872
CAS:
146464-93-9
| Molecular Weight: | 348.36 g./mol | Molecular Formula: | C₁₈H₁₆N₆O₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD09833979 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C |
Product Description:
Used primarily as an intermediate in the synthesis of antifolate agents, this compound plays a key role in the development of certain chemotherapeutic drugs. Its structure allows for targeted inhibition of enzymes involved in folate metabolism, which is critical in rapidly dividing cells. It is especially valuable in research focused on cancer treatment, where it helps design inhibitors that disrupt DNA synthesis in tumor cells. Additionally, it serves as a building block in creating analogs of known drugs to improve efficacy, selectivity, and reduce resistance. Its alkyne functionality enables further modification through click chemistry, facilitating drug conjugation and labeling for diagnostic or delivery purposes.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 100mg | 10-20 days | ฿159,910.00 |
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4-(1-(2,4-Diaminopteridin-6-yl)pent-4-yn-2-yl)benzoicacid
Used primarily as an intermediate in the synthesis of antifolate agents, this compound plays a key role in the development of certain chemotherapeutic drugs. Its structure allows for targeted inhibition of enzymes involved in folate metabolism, which is critical in rapidly dividing cells. It is especially valuable in research focused on cancer treatment, where it helps design inhibitors that disrupt DNA synthesis in tumor cells. Additionally, it serves as a building block in creating analogs of known drugs to improve efficacy, selectivity, and reduce resistance. Its alkyne functionality enables further modification through click chemistry, facilitating drug conjugation and labeling for diagnostic or delivery purposes.
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