5-(1,3-dioxolan-2-yl)-2-fluoroaniline

95%

  • Product Code: 180265
  CAS:    95261-87-3
Molecular Weight: 183.18 g./mol Molecular Formula: C₉H₁₀FNO₂
EC Number: MDL Number:
Melting Point: Boiling Point: 295.6±40.0 °C(Predicted)
Density: 1.294±0.06 g/cm3(Predicted) Storage Condition: Room temperature, seal, dry
Product Description: Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of fluorinated active pharmaceutical ingredients (APIs) where the fluoroaniline moiety enhances metabolic stability and binding affinity. Its masked aldehyde group (as dioxolane) allows for selective transformations in multi-step syntheses, especially in oncology and central nervous system drug candidates. Also employed in agrochemicals for constructing herbicides and fungicides due to its aromatic fluorine contribution to lipophilicity and bioavailability. Suitable for use in cross-coupling reactions and as a building block in combinatorial chemistry.
Sizes / Availability / Pricing:
Size Availability Price Quantity
100mg 10-20 days ฿48,000.00
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5-(1,3-dioxolan-2-yl)-2-fluoroaniline
Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of fluorinated active pharmaceutical ingredients (APIs) where the fluoroaniline moiety enhances metabolic stability and binding affinity. Its masked aldehyde group (as dioxolane) allows for selective transformations in multi-step syntheses, especially in oncology and central nervous system drug candidates. Also employed in agrochemicals for constructing herbicides and fungicides due to its aromatic fluorine contribution to lipophilicity and bioavailability. Suitable for use in cross-coupling reactions and as a building block in combinatorial chemistry.
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