2′-Deoxy-5′-O-DMT-N2-methylguanosine 3′-CE phosphoramidite

  • Product Code: 180441
  CAS:    808132-80-1
Molecular Weight: 783.85 g./mol Molecular Formula: C₄₁H₅₀N₇O₇P
EC Number: MDL Number:
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Density: Storage Condition: Room temperature
Product Description: Widely used in oligonucleotide synthesis, this compound enables the incorporation of modified guanosine into DNA strands. The N2-methylguanosine modification enhances stability and influences base-pairing properties, making it valuable in the development of antisense oligonucleotides, PCR primers, and probes where precise hybridization control is required. The DMT group allows for stepwise chain elongation in solid-phase synthesis by providing reversible protection, while the phosphoramidite group ensures efficient coupling. Its application is critical in research involving gene regulation, nucleic acid therapeutics, and functional genomics.
Sizes / Availability / Pricing:
Size Availability Price Quantity
25mg 10-20 days ฿43,930.00
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2′-Deoxy-5′-O-DMT-N2-methylguanosine 3′-CE phosphoramidite
Widely used in oligonucleotide synthesis, this compound enables the incorporation of modified guanosine into DNA strands. The N2-methylguanosine modification enhances stability and influences base-pairing properties, making it valuable in the development of antisense oligonucleotides, PCR primers, and probes where precise hybridization control is required. The DMT group allows for stepwise chain elongation in solid-phase synthesis by providing reversible protection, while the phosphoramidite group ensures efficient coupling. Its application is critical in research involving gene regulation, nucleic acid therapeutics, and functional genomics.
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