Entrectinib

10mM in DMSO

  • Product Code: 181257
  CAS:    1108743-60-7
Molecular Weight: 560.64 g./mol Molecular Formula: C₃₁H₃₄F₂N₆O₂
EC Number: MDL Number: MFCD28129099
Melting Point: Boiling Point:
Density: Storage Condition: -20°C
Product Description: Used as an anticancer agent targeting tumors with specific genetic alterations involving NTRK gene fusions and ROS1 rearrangements. It is effective in treating solid tumors that have spread or cannot be surgically removed, especially in non-small cell lung cancer and neuroblastoma. Works by inhibiting abnormal tyrosine kinases that drive uncontrolled cell growth. Shows activity in central nervous system tumors due to its ability to cross the blood-brain barrier, making it suitable for cancers with brain metastases. Administered orally, it offers a targeted therapy option for patients with advanced or refractory cancers harboring these molecular markers.
Sizes / Availability / Pricing:
Size Availability Price Quantity
1ml 10-20 days ฿10,970.00
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Entrectinib
Used as an anticancer agent targeting tumors with specific genetic alterations involving NTRK gene fusions and ROS1 rearrangements. It is effective in treating solid tumors that have spread or cannot be surgically removed, especially in non-small cell lung cancer and neuroblastoma. Works by inhibiting abnormal tyrosine kinases that drive uncontrolled cell growth. Shows activity in central nervous system tumors due to its ability to cross the blood-brain barrier, making it suitable for cancers with brain metastases. Administered orally, it offers a targeted therapy option for patients with advanced or refractory cancers harboring these molecular markers.
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