ethyl 4-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)benzoate

98%

  • Product Code: 183452
  CAS:    1192765-24-4
Molecular Weight: 262.109 g./mol Molecular Formula: C₁₄H₁₉BO₄
EC Number: MDL Number:
Melting Point: Boiling Point:
Density: Storage Condition: 2-8℃
Product Description: Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its boronate ester group facilitates efficient coupling with aryl halides under palladium catalysis, making it valuable in constructing biaryl systems found in active pharmaceutical ingredients. The ester functionality allows further derivatization, such as hydrolysis to carboxylic acids or conversion to amides, supporting diverse compound libraries in drug discovery. Stable and compatible with various functional groups, it is favored in late-stage functionalization for its reliability and high yield in complex molecule assembly.
Sizes / Availability / Pricing:
Size Availability Price Quantity
250mg 10-20 days ฿402.00
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1g 10-20 days ฿1,260.00
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25g 10-20 days ฿7,804.50
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-
5g 10-20 days ฿2,255.00
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ethyl 4-(5,5-dimethyl-1,3,2-dioxaborinan-2-yl)benzoate
Used as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in pharmaceutical and agrochemical synthesis. Its boronate ester group facilitates efficient coupling with aryl halides under palladium catalysis, making it valuable in constructing biaryl systems found in active pharmaceutical ingredients. The ester functionality allows further derivatization, such as hydrolysis to carboxylic acids or conversion to amides, supporting diverse compound libraries in drug discovery. Stable and compatible with various functional groups, it is favored in late-stage functionalization for its reliability and high yield in complex molecule assembly.
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