(E)-N'-hydroxy-5-(trifluoromethyl)pyridine-2-carboximidamide
≥95%
- Product Code: 184086
CAS:
175277-44-8
| Molecular Weight: | 205.1373 g./mol | Molecular Formula: | C₇H₆F₃N₃O |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00205809 | |
| Melting Point: | 124-126 °C | Boiling Point: | 328.1 °C at 760mmHg |
| Density: | 1.52 g/cm3 | Storage Condition: | 2-8°C |
Product Description:
Used as a potent inhibitor of histone deacetylases (HDAC), particularly HDAC6, making it valuable in research for cancer therapy and neurodegenerative diseases. It modulates protein acetylation, leading to cell cycle arrest and apoptosis in tumor cells. Commonly employed in preclinical studies to evaluate epigenetic regulation and immune modulation. Also utilized in studies exploring inflammation, autoimmune disorders, and viral latency due to its ability to alter gene expression and protein function. Its hydroxamic acid group enables strong binding to zinc-containing enzymes, enhancing its biological activity.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 250mg | 10-20 days | £156.55 |
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| 100mg | 10-20 days | £96.18 |
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(E)-N'-hydroxy-5-(trifluoromethyl)pyridine-2-carboximidamide
Used as a potent inhibitor of histone deacetylases (HDAC), particularly HDAC6, making it valuable in research for cancer therapy and neurodegenerative diseases. It modulates protein acetylation, leading to cell cycle arrest and apoptosis in tumor cells. Commonly employed in preclinical studies to evaluate epigenetic regulation and immune modulation. Also utilized in studies exploring inflammation, autoimmune disorders, and viral latency due to its ability to alter gene expression and protein function. Its hydroxamic acid group enables strong binding to zinc-containing enzymes, enhancing its biological activity.
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