Ethyl 8-fluoro-4-hydroxy-6-iodoquinoline-3-carboxylate

95%

  • Product Code: 184626
  CAS:    228728-08-3
Molecular Weight: 361.11 g./mol Molecular Formula: C₁₂H₉FINO₃
EC Number: MDL Number: MFCD12922926
Melting Point: Boiling Point:
Density: Storage Condition: Room temperature, seal, dry
Product Description: Used as a key intermediate in the synthesis of fluoroquinolone antibiotics, particularly in the development of potent antimicrobial agents. Its structure allows for further functionalization at the quinoline core, enabling the creation of derivatives with enhanced activity against resistant bacterial strains. Commonly employed in pharmaceutical research to optimize drug candidates targeting DNA gyrase and topoisomerase IV enzymes. Also utilized in medicinal chemistry for structure-activity relationship (SAR) studies to improve pharmacokinetic properties and reduce toxicity in next-generation antibiotics.
Sizes / Availability / Pricing:
Size Availability Price Quantity
100mg 10-20 days ฿330.00
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-
250mg 10-20 days ฿780.00
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1g 10-20 days ฿2,980.00
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Ethyl 8-fluoro-4-hydroxy-6-iodoquinoline-3-carboxylate
Used as a key intermediate in the synthesis of fluoroquinolone antibiotics, particularly in the development of potent antimicrobial agents. Its structure allows for further functionalization at the quinoline core, enabling the creation of derivatives with enhanced activity against resistant bacterial strains. Commonly employed in pharmaceutical research to optimize drug candidates targeting DNA gyrase and topoisomerase IV enzymes. Also utilized in medicinal chemistry for structure-activity relationship (SAR) studies to improve pharmacokinetic properties and reduce toxicity in next-generation antibiotics.
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