Ethyl 8-fluoro-4-hydroxy-6-iodoquinoline-3-carboxylate
95%
- Product Code: 184626
CAS:
228728-08-3
Molecular Weight: | 361.11 g./mol | Molecular Formula: | C₁₂H₉FINO₃ |
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EC Number: | MDL Number: | MFCD12922926 | |
Melting Point: | Boiling Point: | ||
Density: | Storage Condition: | Room temperature, seal, dry |
Product Description:
Used as a key intermediate in the synthesis of fluoroquinolone antibiotics, particularly in the development of potent antimicrobial agents. Its structure allows for further functionalization at the quinoline core, enabling the creation of derivatives with enhanced activity against resistant bacterial strains. Commonly employed in pharmaceutical research to optimize drug candidates targeting DNA gyrase and topoisomerase IV enzymes. Also utilized in medicinal chemistry for structure-activity relationship (SAR) studies to improve pharmacokinetic properties and reduce toxicity in next-generation antibiotics.
Sizes / Availability / Pricing:
Size | Availability | Price | Quantity |
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100mg | 10-20 days | ฿330.00 |
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250mg | 10-20 days | ฿780.00 |
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1g | 10-20 days | ฿2,980.00 |
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Ethyl 8-fluoro-4-hydroxy-6-iodoquinoline-3-carboxylate
Used as a key intermediate in the synthesis of fluoroquinolone antibiotics, particularly in the development of potent antimicrobial agents. Its structure allows for further functionalization at the quinoline core, enabling the creation of derivatives with enhanced activity against resistant bacterial strains. Commonly employed in pharmaceutical research to optimize drug candidates targeting DNA gyrase and topoisomerase IV enzymes. Also utilized in medicinal chemistry for structure-activity relationship (SAR) studies to improve pharmacokinetic properties and reduce toxicity in next-generation antibiotics.
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