5-(Ethylsulfonyl)-1-methyl-1H-tetrazole
98%
- Product Code: 184678
CAS:
1019062-29-3
| Molecular Weight: | 176.2 g./mol | Molecular Formula: | C₄H₈N₄O₂S |
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| Density: | Storage Condition: | Room temperature, seal, dry |
Product Description:
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of sartan-class antihypertensive drugs such as valsartan and irbesartan. Its sulfonyl and tetrazole groups enhance binding affinity to the angiotensin receptor, improving drug efficacy. Also employed in medicinal chemistry for building bioisosteres of carboxylic acids due to the tetrazole ring’s ability to mimic carboxylate functionality while offering better metabolic stability and membrane permeability. Additionally, it finds use in the development of agrochemicals and functional materials where heterocyclic stability and polarity are required.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
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| 1g | 10-20 days | $180.66 |
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| 5g | 10-20 days | $595.25 |
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5-(Ethylsulfonyl)-1-methyl-1H-tetrazole
Used as a key intermediate in the synthesis of angiotensin II receptor antagonists, particularly in the production of sartan-class antihypertensive drugs such as valsartan and irbesartan. Its sulfonyl and tetrazole groups enhance binding affinity to the angiotensin receptor, improving drug efficacy. Also employed in medicinal chemistry for building bioisosteres of carboxylic acids due to the tetrazole ring’s ability to mimic carboxylate functionality while offering better metabolic stability and membrane permeability. Additionally, it finds use in the development of agrochemicals and functional materials where heterocyclic stability and polarity are required.
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