4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-ol
98%
- Product Code: 184961
CAS:
905306-05-0
| Molecular Weight: | 291.30 g./mol | Molecular Formula: | C₁₇H₁₃N₃O₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD28965345 | |
| Melting Point: | 252-254 °C | Boiling Point: | 491.9±45.0 °C(Predicted) |
| Density: | 1.36±0.1 g/cm3(Predicted) | Storage Condition: | Room temperature, seal, dry |
Product Description:
Used as a key intermediate in the synthesis of epidermal growth factor receptor (EGFR) inhibitors, particularly in targeted cancer therapies. Its structure enables selective binding to mutant forms of EGFR, making it valuable in developing drugs for non-small cell lung cancer (NSCLC). The compound's ability to cross the blood-brain barrier enhances its utility in treating brain metastases. It is also employed in medicinal chemistry research to optimize kinase inhibitor potency and selectivity.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.250 G | 10-20 days | ฿5,810.00 |
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4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-ol
Used as a key intermediate in the synthesis of epidermal growth factor receptor (EGFR) inhibitors, particularly in targeted cancer therapies. Its structure enables selective binding to mutant forms of EGFR, making it valuable in developing drugs for non-small cell lung cancer (NSCLC). The compound's ability to cross the blood-brain barrier enhances its utility in treating brain metastases. It is also employed in medicinal chemistry research to optimize kinase inhibitor potency and selectivity.
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