(E)-3-(3-(3,5-Bis(Trifluoromethyl)Phenyl)-1H-1,2,4-Triazol-1-Yl)-2-Bromoacrylamide
98%
- Product Code: 185677
CAS:
1642300-95-5
| Molecular Weight: | 429.12 g./mol | Molecular Formula: | C₁₃H₇BrF₆N₄O |
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| Density: | Storage Condition: | Room temperature |
Product Description:
Used as a potent inhibitor in biochemical research, particularly targeting specific enzymes involved in cellular signaling pathways. It is commonly applied in studies related to protein degradation, including proteolysis-targeting chimeras (PROTACs) and kinase inhibition. Its electrophilic acrylamide group enables covalent binding to cysteine residues in target proteins, enhancing selectivity and prolonging inhibitory effects. Due to its bromine and trifluoromethyl groups, it exhibits high lipophilicity and membrane permeability, making it suitable for cell-based assays. Frequently employed in cancer research for modulating oncogenic proteins and evaluating therapeutic targets.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 G | 10-20 days | ฿19,020.00 |
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| 0.250 G | 10-20 days | ฿31,690.00 |
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| 1.000 G | 10-20 days | ฿77,800.00 |
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(E)-3-(3-(3,5-Bis(Trifluoromethyl)Phenyl)-1H-1,2,4-Triazol-1-Yl)-2-Bromoacrylamide
Used as a potent inhibitor in biochemical research, particularly targeting specific enzymes involved in cellular signaling pathways. It is commonly applied in studies related to protein degradation, including proteolysis-targeting chimeras (PROTACs) and kinase inhibition. Its electrophilic acrylamide group enables covalent binding to cysteine residues in target proteins, enhancing selectivity and prolonging inhibitory effects. Due to its bromine and trifluoromethyl groups, it exhibits high lipophilicity and membrane permeability, making it suitable for cell-based assays. Frequently employed in cancer research for modulating oncogenic proteins and evaluating therapeutic targets.
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