(E)-4,4,5,5-Tetramethyl-2-(3-((tetrahydro-2H-pyran-2-yl)oxy)prop-1-en-1-yl)-1,3,2-dioxaborolane

95%(stabilized with MEHQ)

  • Product Code: 185712
  CAS:    642066-70-4
Molecular Weight: 268.16 g./mol Molecular Formula: C₁₄H₂₅BO₄
EC Number: MDL Number: MFCD03788736
Melting Point: Boiling Point:
Density: Storage Condition: -20°C, Sealed, Drying, Inert Gas
Product Description: Used as a key intermediate in organic synthesis, particularly in cross-coupling reactions such as Suzuki-Miyaura coupling. Its main application lies in the construction of complex organic molecules, including pharmaceuticals and agrochemicals, where it enables the formation of carbon-carbon bonds. The tetrahydropyranyl (THP) protecting group stabilizes sensitive functionalities during reaction sequences, allowing selective transformations. After coupling, the THP group can be easily removed under mild acidic conditions, making this compound valuable in multi-step syntheses requiring precise functional group control. It is especially useful in the preparation of bioactive compounds and conjugated systems in medicinal chemistry and materials science.
Sizes / Availability / Pricing:
Size Availability Price Quantity
0.250 G 10-20 days £98.45
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1.000 G 10-20 days £279.29
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5.000 G 10-20 days £1,303.11
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(E)-4,4,5,5-Tetramethyl-2-(3-((tetrahydro-2H-pyran-2-yl)oxy)prop-1-en-1-yl)-1,3,2-dioxaborolane
Used as a key intermediate in organic synthesis, particularly in cross-coupling reactions such as Suzuki-Miyaura coupling. Its main application lies in the construction of complex organic molecules, including pharmaceuticals and agrochemicals, where it enables the formation of carbon-carbon bonds. The tetrahydropyranyl (THP) protecting group stabilizes sensitive functionalities during reaction sequences, allowing selective transformations. After coupling, the THP group can be easily removed under mild acidic conditions, making this compound valuable in multi-step syntheses requiring precise functional group control. It is especially useful in the preparation of bioactive compounds and conjugated systems in medicinal chemistry and materials science.
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