(4S)-3-(9H-fluoren-9-ylmethoxycarbonyl)-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid

98%

  • Product Code: 186733
  CAS:    141636-66-0
Molecular Weight: 383.46 g./mol Molecular Formula: C₂₁H₂₁NO₄S
EC Number: MDL Number: MFCD02682321
Melting Point: 65-73 °C Boiling Point:
Density: Storage Condition: 2-8°C, sealed, dry
Product Description: Widely used in peptide synthesis as a chiral auxiliary and protecting group carrier, this compound enables stereoselective construction of complex peptides. The thiazolidine ring acts as a scaffold for amino acid assembly, while the fluorenylmethoxycarbonyl (Fmoc) group provides orthogonal protection for the amine functionality, allowing stepwise chain elongation in solid-phase peptide synthesis. Its rigid structure helps control stereochemistry during coupling reactions, improving yield and purity. Commonly employed in the preparation of biologically active peptides and peptidomimetics, it supports the synthesis of pharmaceuticals and biochemical probes. The compound’s stability under various reaction conditions and clean deprotection profile make it valuable in automated and high-throughput peptide manufacturing.
Sizes / Availability / Pricing:
Size Availability Price Quantity
250mg 10-20 days ฿10,370.00
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1g 10-20 days ฿20,720.00
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(4S)-3-(9H-fluoren-9-ylmethoxycarbonyl)-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid
Widely used in peptide synthesis as a chiral auxiliary and protecting group carrier, this compound enables stereoselective construction of complex peptides. The thiazolidine ring acts as a scaffold for amino acid assembly, while the fluorenylmethoxycarbonyl (Fmoc) group provides orthogonal protection for the amine functionality, allowing stepwise chain elongation in solid-phase peptide synthesis. Its rigid structure helps control stereochemistry during coupling reactions, improving yield and purity. Commonly employed in the preparation of biologically active peptides and peptidomimetics, it supports the synthesis of pharmaceuticals and biochemical probes. The compound’s stability under various reaction conditions and clean deprotection profile make it valuable in automated and high-throughput peptide manufacturing.
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