Fmoc-Glu(EDANS)-OtBu
≥90%
- Product Code: 186754
CAS:
194039-49-1
| Molecular Weight: | 673.78 g./mol | Molecular Formula: | C₃₆H₃₉N₃O₈S |
|---|---|---|---|
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| Density: | Storage Condition: | Room temperature |
Product Description:
Used in fluorescence-based studies of peptide structure and dynamics, this compound serves as a key building block in solid-phase peptide synthesis where the EDANS fluorophore acts as a fluorescent donor in FRET (Förster resonance energy transfer) assays. Its incorporation into peptide sequences allows real-time monitoring of enzymatic activity, such as protease cleavage, due to the change in fluorescence upon separation from a quenching moiety. The Fmoc group enables stepwise synthesis by providing temporary N-terminal protection, while the tert-butyl ester protects the glutamic acid side chain, ensuring selective deprotection and minimal side reactions. Commonly applied in developing biosensors, diagnostic probes, and studying protein-protein interactions.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 25mg | 10-20 days | Ft97,244.08 |
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Fmoc-Glu(EDANS)-OtBu
Used in fluorescence-based studies of peptide structure and dynamics, this compound serves as a key building block in solid-phase peptide synthesis where the EDANS fluorophore acts as a fluorescent donor in FRET (Förster resonance energy transfer) assays. Its incorporation into peptide sequences allows real-time monitoring of enzymatic activity, such as protease cleavage, due to the change in fluorescence upon separation from a quenching moiety. The Fmoc group enables stepwise synthesis by providing temporary N-terminal protection, while the tert-butyl ester protects the glutamic acid side chain, ensuring selective deprotection and minimal side reactions. Commonly applied in developing biosensors, diagnostic probes, and studying protein-protein interactions.
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